Penilaian Perlemakan Hati pada Pasien Obesitas Menggunakan Pencitraan MRI

Abstract

Non-invasive imaging tools have been used to qualify and quantify liver fat content. Several MRI-based techniques have been used to detect and quantify fat and water content in the liver, including the Dixon method (in-phase and out-of-phase images), frequency-selective imaging, and MRI spectroscopy. Evidence of hepatic steatosis must be seen on imaging or histology to diagnose NAFLD, and other causes of hepatic disease or steatosis must be excluded.

Magnetic Resonance Imaging (MRI) is an accurate method for assessing and monitoring fat content in the liver. In various new quantitative MRI methods, T2/T2∗ sequence is used to measure the amount of iron, Magnetic Resonance Elastography (MRE) to assess liver stiffness through mechanical shear waves that cause vibrations in the parenchyma, proton density fat fraction (PDFF) to show distribution fat in the parenchyma by measuring the chemical shift between fat and water, and diffusion-weighted imaging (DWI) to measure the movement of molecules in tissue. Liver T1 mapping techniques have the potential to differentiate steatotic from nonsteatotic livers, and T1 values ​​appear to have a strong correlation with liver fat content..